Therapeutic efficacy of liraglutide on diabetic nephropathy mice by inhibiting inflammatory factors
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منابع مشابه
Effect of Consumption of Honey Containing Bacillus coagulans on Inflammatory and Oxidative Stress Factors in Patients with Diabetic Nephropathy
Background and Objectives: Diabetic nephropathy is one of the dangerous complications of diabetes, which has a relatively high incidence in diabetic patients and causes kidney failure. The aim of this study was to investigate the effect of probiotic honey consumption on inflammatory and oxidative stress indices in patients with diabetic nephropathy. Methods: This randomized, double-blind, co...
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OBJECTIVE Though increasing evidences showed that statins had potential benefits to diabetic kidney disease (DKD), its mechanism has not been completely elucidated yet. The aim of this study was to investigate the renoprotective effects of atorvastatin on DKD. MATERIALS AND METHODS Kidney injury was induced by streptozotocin (STZ) in rats. STZ-diabetic rats were treated with atorvastatin (10 ...
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OBJECTIVE ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type I repeats-13) prevents microvascular thrombosis by cleaving prothrombogenic ultralarge von Willebrand factor (VWF) multimers. Clinical studies have found association between reduced ADAMTS13-specific activity, ultralarge VWF multimers, and thrombotic angiopathy in patients with diabetic nephropathy. It remains unknow...
متن کاملEndogenous Nampt upregulation is associated with diabetic nephropathy inflammatory-fibrosis through the NF-κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory-fibrosis by inhibiting endogenous Nampt
Nicotinamide phosphoribosyltransferase (Nampt) is a key enzyme in the nicotinamide adenine dinucleotide (NAD+) biosynthetic pathway. Exogenous extra cellular Nampt has been reported to increase the synthesis of pro-fibrotic molecules in various types of renal cells. However, the role of endogenous Namptenzymatic activity in diabetic renal cells, particularly those associated with inflammation a...
متن کاملRisk Factors for Diabetic Nephropathy in Diabetic Patients
Aims: Diabetic nephropathy is one of the consequences of type 1 and type 2 diabetes and one of the main causes of End-Stage Renal Disease (ESRD) as well as an important risk factor for cardiovascular morbidity and death. The aim of this study was to identify the risk factors for diabetic nephropathy in diabetic patients. Instruments & Methods: In this cross-sectional descriptive study, 121 pat...
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ژورنال
عنوان ژورنال: European Journal of Inflammation
سال: 2018
ISSN: 2058-7392,2058-7392
DOI: 10.1177/2058739218819283